What is MIGRAKET? – ProLongevity

MIGRAKET is a remarkable medical food developed specifically for people suffering from migraines. Rather than relying on painkillers, generic dietary supplements, or strong prescription-only medications to suppress the symptoms of migraine, MIGRAKET takes a fundamentally different approach: it supports the brain’s metabolism by providing an alternative fuel source (ketones) along with key micronutrients shown to reduce the frequency and severity of migraines. This blog explores how MIGRAKET works, why it was developed, and how it fits into a comprehensive, lifestyle-first migraine management strategy like the one offered by ProLongevity.

Introduction to MIGRAKET

As we discussed in one of our recent blogs Migraines aren’t just headaches. They’re debilitating neurological events, often accompanied by nausea, visual disturbances, sensitivity to light and sound, and in many cases, an overwhelming sense of dread. For the millions of people globally affected by migraines, conventional treatments often fall short.

Enter MIGRAKET: a Swiss-engineered “medical food” that targets a root cause of migraines—an energy deficit in the brain. Developed by Dr Elena Gross, herself a chronic migraine sufferer and Oxford-trained neuroscientist, MIGRAKET is based on cutting-edge research into how the brain uses fuel, especially when it’s under metabolic stress. Dr Gross was a guest on a recent episode of the ProLongevity podcast

 

 

The Origin and Meaning of MIGRAKET

The name says it all: MIGRAKET = Migraine + Ketones.

Dr Elena Gross coined the term while working on her PhD in neuro-metabolism at Oxford University.  She discovered that many migraineurs suffer from impaired glucose metabolism in the brain. This “brain energy gap” makes neurons more excitable and more vulnerable to common migraine triggers such as sleep deprivation, fasting, stress, or even hormonal fluctuations.

By supplying ketones (specifically bio-identical D-beta-hydroxybutyrate) MIGRAKET offers the brain a more efficient and resilient fuel source. It’s not a treatment in the traditional pharmaceutical sense, but a tool to prevent migraines by addressing one of their most common root causes.

Key Features and Functionality

MIGRAKET is a powdered drink mix that you dissolve in water, taken twice daily. Each sachet contains:

• 4.3g D-beta-hydroxybutyrate (BHB): a ketone body that crosses the blood-brain barrier and fuels neurons directly.. it’s the same keto-brain-fuel that our bodies produce naturally
• Magnesium: essential for nerve function and a known migraine preventative
• Coenzyme Q10: supports mitochondrial function
• Riboflavin (B2) and Vitamin B12: shown to reduce migraine frequency in clinical studies
• Electrolytes and Antioxidants: to support hydration and reduce oxidative stress

MIGRAKET is classed as a “medical food” in Europe and the US, meaning it is intended for the dietary management of a disease or condition under medical supervision.

How MIGRAKET Works

In simple terms: MIGRAKET fuels your brain when glucose fails you.

During periods of stress, fasting, poor sleep, or hormonal flux, the brain’s glucose supply may fall short. For some individuals, especially migraine sufferers, this creates an energy crisis that can trigger a cascade of neuronal hyperexcitability, inflammation, and blood vessel instability. If all of that sounds very like epilepsy there’s a reason. It’s a little-known fact that migraine and epilepsy are closely related.

Ketones bypass this problem. They provide:

• An immediate alternative to glucose
• Stabilisation of neuronal firing
• Reduced glutamate toxicity and CGRP signalling
• Anti-inflammatory and antioxidant benefits

MIGRAKET delivers ketones directly, so you don’t have to fast, follow a strict ketogenic diet, or wait days for your body to enter ketosis.

For those interested in ketogenic diets as a broader strategy, check out our complete guide to keto.

Benefits of Using MIGRAKET

Backed by peer-reviewed research and real-world testimonials, MIGRAKET offers multiple benefits:

• Reduces migraine frequency: Preliminary studies suggest up to 60% reduction
• Improves quality of life: Less reliance on acute medications, fewer days lost to illness
• Enhances mitochondrial health: Supports long-term brain resilience
• Safe and well-tolerated: Minimal side effects when taken as directed

At ProLongevity, we’ve seen clients use MIGRAKET alongside CGM, low-carb diets, and sleep coaching with the aim of dramatically reducing their migraines.

Use Cases and Applications

MIGRAKET is designed for:

• Chronic migraineurs (15+ headache days per month)
• People with episodic migraines who want to avoid progression
• Women with hormonal migraines
• Patients with medication overuse headaches
• People sensitive to fasting or skipping meals

It can be used alone or as part of a multimodal strategy including dietary changes, blood sugar monitoring (e.g. CGM), sleep hygiene, and stress reduction.

MIGRAKET vs. Similar Solutions

Feature	MIGRAKET	Ketogenic Diet	OTC Supplements
Fuel source	Exogenous ketones	Endogenous ketones	None
Clinically tested	Yes	Indirectly	Rarely
Medical supervision	Recommended	Not required	Not required
Ease of use	High	Moderate to difficult	Easy
Fast onset	Within 30 mins	Several days	Variable

MIGRAKET combines the therapeutic potential of nutritional ketosis with the practicality of a daily supplement.

Challenges and Limitations

Like all interventions, MIGRAKET isn’t perfect.

• Cost: At around £90/month, it’s more expensive than most supplements
• Compliance: Should  be taken twice daily, ideally 12 hours apart
• Taste: Some users report a metallic or salty flavour
• Not a cure-all: Works best when combined with lifestyle interventions

At ProLongevity, we integrate MIGRAKET into bespoke plans that include:

• Keto support
• Sleep optimisation
• Stress reduction
• Supplement protocols

Future Prospects for MIGRAKET:

Dr Elena Gross and her team at KetoSwiss are currently researching MIGRAKET’s potential in:

• Cluster headaches
• Cognitive decline / Alzheimer’s
• Long COVID-related fatigue
• Mental health disorders with a mitochondrial link (e.g. bipolar, depression)

As the science of brain metabolism evolves, MIGRAKET may become a frontline nutritional therapy not just for migraine, but for a host of neuroenergetic disorders.

Conclusion

MIGRAKET represents a new paradigm in migraine care. Rather than suppressing symptoms, it addresses one of the condition’s root causes: impaired brain energy metabolism.

For anyone tired of cycling through medications, suffering side effects, or losing days to pain, MIGRAKET offers hope. And at ProLongevity, we’re here to guide you through the process: from understanding your personal metabolic triggers to building a life where migraines no longer call the shots.

Ready to take the next step? Book your free discovery call and find out if MIGRAKET and our migraine programme are right for you or someone you love.

Migraket: backed by research. Driven by experience. Powered by ketones.